246-TRICHLOROANISOLE

← Back to Chemical Safety

Basic information

  • Chemical formula(s): \({\rm C_7H_5Cl_3O}\)
  • Other names: 1,3,5-trichloro-2-methoxybenzene, 2,4,6-trichloromethoxybenzene, TCA, tyrene
  • CAS: 87-40-1
  • International Chemical Safety Card (ICSC): N/A (see Sigma Aldrich safety data sheet)
  • Flammability:
  • Description:

NFPA 704 (fire diamond)

  • Health (blue): 2 - intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury.
  • Flammability (red): 0 - will not burn under typical fire conditions, will not burn in air unless exposed to a temperature of 820 °C for more than 5 minutes.
  • Instability–reactivity (yellow): 0 - normally stable, even under fire exposure conditions, and is not reactive with water.
  • Special notice (white): -

Hazard statements

Code Phrase
H302 harmful if swallowed
H319 causes serious eye irritation
H413 may cause long lasting harmful effects to aquatic life

Precautionary statements

Code Phrase
P264 wash … thoroughly after handling
P270 do not eat, drink or smoke when using this product
P273 avoid release to the environment
P280 wear protective gloves/protective clothing/eye protection/face protection
P301+P312 IF SWALLOWED: call the ETH Emergency Desk: +41 44 342 11 88 (from mobile) or 888 (from landline)
P305+P351+P338 IF IN EYES: rinse continuously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing
P330 rinse mouth
P337+P313 IF EYE IRRITATION PERSISTS: get medical advice/attention
P501 dispose of contents/container to HCI-Shop

Protective measures

Gloves

Occupational Safety and Health Act of 1970 and OSHA Glove Selection Chart do not provide recommendation on gloves for handling 2,4,6-trichloroanisole. Sigma Aldrich provides the following information:

  • Neoprene: N/A
  • Natural latex or rubber: N/A
  • Buthyl: N/A
  • Nitrile: very good protection; 480 min breakthrough time for 0.11 mm thickness.

Safety goggles

  • Always wear safety goggles when handling 2,4,6-trichloroanisole. Corrective glasses are not considered safety googles.
  • Handle 2,4,6-trichloroanisole inside the fume hood only (with exception of moving the closed bottle to and from the storage cabinet).

Clothing

  • Wear long trousers and fully covered shoes.
  • Contact lenses are forbidden while working with chemical substances, even in combination with safety glasses.
  • Do not wear cosmetics.
  • Do not wear synthetic clothing while working with flammable liquids or gases or when a hazard is present as these materials tend to melt and stick to exposed skin.
  • Do not wear headphones.

Spill management

  • Use personal protective equipment.
  • Avoid dust formation, avoid breathing dust.
  • Avoid breathing vapors or mist.
  • Ensure adequate ventilation.
  • Evacuate personnel to safe areas.
  • Sweep up without creating dust and arrange disposal.
  • Do not let it enter drain.
  • If a spill happened outside the fume hood (on the floor or desktop) contact Dr Jakub Tkaczuk (+41 44 632 31 62) and the ETH Emergency Desk (+41 44 342 11 88 from mobile or 888 from landline).